Messenger rna stocks12/16/2023 ![]() ![]() Imagine, he said, that Henry Ford was rolling the first Model T off the production line, only to be told the world needed a billion of them.Īs they found, cells are packed with sensing molecules that distinguish your RNA from that of a virus. Moderna had promised to make up to a billion doses during 2021. When I spoke to Moderna CEO Stéphane Bancel in December, just before the US Food and Drug Administration authorized his company’s vaccine, he was feeling confident about the shot but worried about making enough of it. Because there’s never been a messenger RNA drug on the market before, there was no factory to commandeer and no supply chain to call on. Unlike most biotech drugs, RNA is not made in fermenters or living cells-it’s produced inside plastic bags of chemicals and enzymes. Inside of six weeks, Moderna had chilled doses ready for tests in animals. Scientists at Moderna, a biotech specializing in messenger RNA, were able to design a vaccine on paper in 48 hours, 11 days before the US even had its first recorded case. It arrived in Mainz at the headquarters of BioNTech, and in Cambridge at Moderna, where some researchers got the readout as a Microsoft Word file. But the genetic information moved even faster. The virus was already moving quickly, jumping onto airplanes and popping up in Hong Kong and Thailand. Chinese government censors at first sought to cover up the outbreak, but on January 10, 2020, a Shanghai scientist posted the germ’s genetic code online through a contact in Australia. Then, in December 2019, the first reports emerged from Wuhan, China, about a scary transmissible pneumonia, most likely some kind of bat virus. ![]()
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